Three genes determine the carboxin sensitivity of mitochondrial succinate oxidation inAspergillus nidulans
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چکیده
منابع مشابه
Studies on the binding of carboxin analogs to succinate dehydrogenase.
Carboxin (5,6-dihydro-2-methyl-l,4-oxathiin-3-carboxanilide) and a number of other carboxanilides are known to be potent inhibitors of succinate oxidation in membrane preparations from animal tissues, fungi, and bacteria, acting at the succinate dehydrogenase-coenzyme Q junction. The kinetics and the maximal extent of inhibition of succinate oxidation by carboxanilides and by thenoyltrifluoroac...
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state 4 and state 3 conditions was studied with corn shoot mitochondria. Comparisons were made.' usin malate and succinate as'-substrates. The inhibitors, rotenone, amvtal. antimycin A andcyanide, inhibited oxidation of NADH in state 3 but rotenone and amytal did not inhibit oxidation in state 4. The inhibition by antimycin A was partially overcome by the presence of cytochrome c. The results i...
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The enthalpy changes for phosphorylating and nonphosphorylating mitochondrial oxidation of succinate by ferricyanide were studied by heatburst microcalorimetry. The enthalpy change observed with a nonphosphorylating system involving sonically disrupted mitochondria agreed with the calculated enthalpy change. The enthalpy changes for phosphorylating and uncoupled systems involving intact mitocho...
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1. Exposure of rats to low environmental temperature resulted in increased activities of several hepatic oxidative-enzyme systems. 2. Simultaneous with increase in liver ubiquinone in cold-exposed rats, the ubiquinone-dependent succinate-neotetrazolium chloride reductase activity also increased. Such an increase could also be obtained by enriching liver with ubiquinone by feeding with an exogen...
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A bstract. Mitochondria from tomato fruit (Lycopes sicon esculentum Mill.) exhibited a respiratory control ratio of 2.5 and an ADP:O ratio of 1.3 for succinate oxidati-on for 24 hours after isolation. They also showed a delay in response to the first addition of ADP. The addition of ATP and ADP before succinate eliminated the delayed response as did chelation of endogenous cations with ethylene...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1975
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300016098